SignaLyte is a dual-practice consultancy combining neurological signal analysis with deep molecular biology expertise — serving pharma, biotech, and medical device companies worldwide.
From clinical trial biomarker design to AI-driven seizure detection — SignaLyte covers the full spectrum of medical signal analysis needs for pharma, biotech, and device companies.
Design and implement quantitative EEG biomarker strategies for CNS drug development, including protocol development, centralised EEG analysis, and regulatory endpoint support.
Pharma / BiotechCustom AI-powered seizure detection pipelines combining Hilbert envelope analysis with deep learning — validated on real clinical EEG data (EDF/BDF) across multiple electrode configurations.
Medical DevicesNeurophysiological biomarker analysis for Alzheimer's disease and related neurodegeneration — including longitudinal signal tracking, group comparison, and AD-specific EEG feature extraction.
Pharma / ResearchEnd-to-end qEEG pipeline development: band power analysis, spectral decomposition, entropy measures, coherence analysis, and time-frequency methods with publication-ready outputs.
Research / ClinicalIntegrated analysis across EEG, ECG, EMG, and EOG — enabling comprehensive neurological and autonomic profiling for complex clinical research and device validation studies.
Multi-modalExpert-led workshops on EEG signal analysis, quantitative EEG, and AI/ML for biosignals — for clinical teams, device engineers, and pharmaceutical researchers.
EducationGrounded in published NIH and UCF research spanning HPV virology, cancer metabolism, polyamine biology, and prodrug design — we bring bench-level molecular expertise to your drug discovery and gene therapy programmes.
Expert consulting on gRNA design, PAM selection, in silico off-target prediction using CFD/MIT scoring, and Cas9/Cas12 variant selection for therapeutic and research applications.
Gene Therapy / Biotech High YieldEnd-to-end strategy for base editing, prime editing, or HDR-based correction — including vector selection (AAV, LNP, RNP), editing efficiency optimisation, and cell model selection.
Gene Therapy High YieldDeep expertise in papillomavirus E2 protein–host chromosome interactions, genome tethering mechanisms, and viral persistence — applicable to AAV and episomal vector design for gene therapy.
Gene Therapy / VirologyConsulting on amino acid transporter (LAT1/SLC7A5) biology, methionine depletion strategies, SAM/polyamine pathway modulation, and autophagy as anti-cancer mechanisms — directly from published pancreatic cancer research.
Oncology / Drug Discovery High YieldExpert advice on spermine/spermidine biosynthesis, ODC/SAMDC/SMS inhibition strategies, and polyamine analogue design for cancer, rare disease, and neurological indications.
Drug DiscoveryExtensive experience in promt engineering for molecular biology/ virology related research and development. Monitoring of LLM outputs in medical and molecular biology research
CRO / ResearchTwo independent PhD-level consultants — each a domain authority — combining to offer uniquely broad expertise across neurological signals and molecular biology.
Dr. Gireesh Neurologist (MD), with PhD in Computer Engineering with specialisation in EEG biomarkers, seizure detection, and neurophysiological signal processing. He combines deep signal processing expertise with AI/ML algorithm development, having developed and validated proprietary seizure detection and Alzheimer's disease analysis pipelines on real clinical datasets.
Dr. Sekhar is a molecular and cell biologist with a research career spanning the NIH (National Institute of Allergy and Infectious Diseases, Bethesda) and the University of Central Florida College of Medicine. Her expertise spans HPV/papillomavirus molecular biology, cancer metabolism (LAT1, methionine/SAM/polyamine pathways), redox-sensitive prodrug design, and CRISPR-adjacent gene-regulatory research. She has published in Journal of Virology, Biomolecules, and Journal of Medicinal Chemistry.
SignaLyte is a boutique consultancy built on the principle that world-class scientific expertise should be accessible to any company, regardless of size. We bring research-grade rigour to commercial problems — without the overhead of a large organisation.
Every SignaLyte engagement — whether in signal analysis or molecular biology — follows a structured, transparent process designed to deliver maximum value with minimum friction.
Whether you need EEG biomarker expertise, CRISPR strategy, cancer metabolism consulting, or prodrug design input — initial consultations are always free.